Nilotinib
Brand name: Tasigna
Description
Tasigna effectively inhibits the tyrosine kinase activity of the BCR-ABL oncoprotein of cell lines and leukemia cells primarily positive on the Philadelphia chromosome
Availability: Prescription needed
Pregnancy: Consult a doctor
Alcohol: Not detected with light alcohol consumption
Side Effects: Nausea, Itching, Skin Rash, Increased Urination
Interactions: Pantoprazole, Hepatic Impairment, Fluid Retention
For informational purposes only. Consult your local medical authority for advice.
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What should I avoid while taking nilotinib?
Grapefruit may interact with nilotinib and lead to unwanted side effects. Avoid the use of grapefruit products.
Avoid taking a stomach acid reducer (such as Pepcid, Tagamet, or Zantac) within 10 hours before or 2 hours after you take nilotinib.
Avoid taking an antacid that contains aluminum, magnesium, or simethicone (such as Di-Gel, Gaviscon, Maalox, Milk of Magnesia, Mylanta, or Rolaids) within 2 hours before or 2 hours after you take nilotinib.
Nilotinib can pass into body fluids (urine, feces, vomit). Caregivers should wear rubber gloves while cleaning up a patient's body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.
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